Resonancia Magnética Funcional: Comportamiento de las áreas elocuentes motoras en gliomas de bajo y alto grado

Jorge R. Do Campo; Marcelo  Cabrini; Ingrid Martín; Carlos  Castillo; Carlos Morales; Claudio Bruno

doi:10.47924/neurotarget2010302

Authors

Jorge R. Do Campo Scientific Foundation of the South, Lomas De Zamora, Buenos Aires, Argentina.
Marcelo Cabrini Hospital Virgen De Altagracia, Ciudad Real, España.
Ingrid Martín Scientific Foundation of the South, Lomas De Zamora, Buenos Aires, Argentina.
Carlos Castillo Scientific Foundation of the South, Lomas De Zamora, Buenos Aires, Argentina.
Carlos Morales Scientific Foundation of the South, Lomas De Zamora, Buenos Aires, Argentina.
Claudio Bruno Scientific Foundation of the South, Lomas De Zamora, Buenos Aires, Argentina.

DOI:

https://doi.org/10.47924/neurotarget2010302

Keywords:

glioma, functional MR imaging, motor paradigms, eloquent area

Abstract

Objectives: To show iconographic examples of the different types of compromise of eloquent motor areas in the assessment of low and high grade fron- toparietal tumors.
Material and methods: Eight patients were selected, 6 males and 2 females, who underwent functional magnetic resonance imaging as part of the presurgical evaluation. Bilateral and unilateral motor paradigms were applied to assess the primary and supplementary eloquent motor areas. The studies were performed on a 1.5T scanner.
Results: The eloquent motor areas are: primary or Rolandic motor area, and supplementary motor area. Functional magnetic resonance imaging allows to identify the eloquent motor areas, and shows BOLD contrast activation (oxygen consumption) during the performance of a motor paradigm. An eloquent area is that which consumes the highest amount of oxygen during the performance of a specific stimulus (paradigm). In low-grade tumors, due to their slow growth and brain plasticity, migration of the eloquent area adjacent to the lesion is identified. In high-grade expansion processes, compromise of the eloquent areas and activation of intra tumor BOLD contrast are identified, due of their fast growth.
Conclusion: Assessment of eloquent motor areas in patients with primary expansion processes is highly useful to plan any surgical action. Low-grade expansion processes generally produce migration of the eloquent motor areas while high-grade tumors compromise them.

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