Refractory temporal epilepsy due to dual pathology: Report of a case

Authors

  • Julio César Suárez Functional Neurosurgery Unit, Neurosurgery Service, Sanatorio Allende, Córdoba. Argentina.
  • Juan Carlos Bulacio CETES. Center for the Study and Treatment of Epilepsy and Sleep, Córdoba. Argentina.
  • Zenón Milciades Sfaello CETES. Center for the Study and Treatment of Epilepsy and Sleep, Córdoba. Argentina.
  • Juan Carlos Viano Functional Neurosurgery Unit, Neurosurgery Service, Sanatorio Allende, Córdoba. Argentina.
  • Enrique José Herrera Functional Neurosurgery Unit, Neurosurgery Service, Sanatorio Allende, Córdoba. Argentina.
  • María Soledad Suárez Functional Neurosurgery Unit, Neurosurgery Service, Sanatorio Allende, Córdoba. Argentina.

DOI:

https://doi.org/10.47924/neurotarget2008421

Keywords:

intractable epilepsy, mesial temporal sclerosis, cortical dysplasia, dual pathology

Abstract

The case of a 23-year-old patient with temporal epilepsy since 9 months of age is described; She remained asymptomatic for some years but the epilepsy recurred at age 15 and she subsequently became refractory to pharmacological treatment. She was studied with brain MRI and video-EEG that showed the left temporal origin of the refractory epilepsy, caused by temporal polar cortical dysplasia and the presence of ipsilateral hippocampal sclerosis. The patient underwent a left anterior temporal lobectomy, with an excellent postoperative evolution, since since then she has had no seizures and is currently not receiving anticonvulsant medication.
Likewise, a review of the literature on refractory temporal epilepsy due to dual pathology in pediatric patients is carried out.

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References

Wyllie E, Comair YG, Kotagal P, Bulacio J, Bingaman W, Ruggieri P. Seizure outcome after epilepsy surgery in children and adolescents. Ann Neurol. 1998;44(5):740-8.

Mikati MA, Holmes GL. Temporal lobe epilepsy. In: Wyllie E, editor. The treatment of epilepsy: Principles and practice. Philadelphia: Lea & Febiger; 1993. p. 513-24.

Wyllie E, Chee M, Granström ML, DelGiudice E, Estes M, Comair Y, et al. Temporal lobe epilepsy in early childhood. Epilepsia. 1993;34(5):859-68.

Cavazzuti GB. Epidemiology of different types of epilepsy in school age children of Modena, Italy. Epilepsia. 1980;21(1):57-62.

Cowan LD, Bodensteiner JB, Leviton A, Doherty L. Prevalence of the epilepsies in children and adolescents. Epilepsia. 1989;30(1):94-106.

Hauser WA, Kurland LT. The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1967. Epilepsia. 1975;16(1):1-66.

Wieser HG, Engel JJ, Williamson PD, Babb TL, Gloor P. Surgically remediable temporal lobe syndromes. In: Engel J Jr, editor. Surgical treatment of the epilepsies. New York: Raven; 1993. p. 49-63.

Gurd A, Bulacio J, Najm I, Bingaman W, Comair Y, Foldvary-Schaefer N, et al. Seizure outcome after temporal lobectomy in 381 adult patients: The Cleveland Clinic experience (1991-2001). Epilepsia. 2002; 43(Supp 7):325.

Shinnar S, Berg AT, Moshé SL, Petix M, Maytal J, Kang H, Goldensohn ES, Hauser WA. Risk of seizure recurrence following a first unprovoked seizure in childhood: a prospective study. Pediatrics. 1990;85(6):1076-85.

Collaborative Group for Epidemiology of Epilepsy. Adverse reactions to antiepileptic drugs: a follow-up study of 355 patients with chronic antiepileptic drug treatment. Epilepsia. 1988;29(6):787-93.

Vining EP, Mellitis ED, Dorsen MM, Cataldo MF, Quaskey SA, Spielberg SP, et al. Psychologic and behavioral effects of antiepileptic drugs in children: a double-blind comparison between phenobarbital and valproic acid. Pediatrics. 1987;80(2):165-74.

Wyllie E, Rothner AD, Lüders H. Partial seizures in children: clinical features, medical treatment, and surgical considerations. Pediatr Clin North Am. 1989;36(2):343-64.

Spencer SS: Selection of candidates for temporal lobe resection. In: Wyllie E, editor. The treatment of epilepsy: Principles and practice. Baltimore: Williams & Wilkins; 1997. p. 967-75.

Babb TL, Brown WJ. Pathological findings in epilepsy. In: Engel J Jr, editor. Surgical treatment of the epilepsies. New York: Raven; 1987. p. 511-40.

Li LM, Cendes F, Andermann F, Watson C, Fish DR, Cook MJ, et al. Surgical outcome in patients with epilepsy and dual pathology. Brain. 1999;122 ( Pt 5):799-805.

Watanabe K, Negoro T, Aso K, Maeda N, Ohki T, Hayakawa F. Childhood onset epilepsy due to focal cortical dysplasia. In: Guerrini R, Andermann F, Canapicchi R, Roger J, Zifkin BG, Pfanner P, editors. Dysplasias of cerebral cortex and epilepsy. Philadelphia: Lippincott-Raven; 1996. p. 227-34.

Barkovich AJ, Kjos BO. Nonlissencephalic cortical dysplasias: correlation of imaging findings with clinical deficits. AJNR Am J Neuroradiol. 1992;13(1):95-103.

Mathern GW, Babb TL, Armstrong DL. Hippocampal sclerosis. In: Engel J Jr., Pedley TA, editors. Epilepsy: a comprehensive textbook. Philadelphia: Lippincott-Raven; 1997. p. 133-55.

Published

2008-05-01

How to Cite

1.
Suárez JC, Bulacio JC, Sfaello ZM, Viano JC, Herrera EJ, Suárez MS. Refractory temporal epilepsy due to dual pathology: Report of a case. NeuroTarget [Internet]. 2008 May 1 [cited 2024 Nov. 21];3(1):22-6. Available from: https://neurotarget.com/index.php/nt/article/view/421

Issue

Section

Case Report