Spinal cord stimulation for angina pectoris: Remote observations

Authors

  • Oscar Alberto Stella Spanish Hospital of Buenos Aires. Argentina

DOI:

https://doi.org/10.47924/neurotarget2009316

Keywords:

angina pectoris, angor pectoris, spinal cord stimulation, coronary X syndrome

Abstract

Background: Chronic refractory angina pectoris is defined as chest pain for heart failure that can not be controlled by regular medication nor by revascularization techniques but by spinal cord stimulation (SCS).

Materials and method: Between 1999 and 2000 three patients with ages between 52 and 62 and placed in classes III and IV, as the New York Heart Association Functional Class (NYHA-FC), were undergone to spinal cord stimulation with an electrode tetrapolar type “paddle” placed in the epidural space at T1, left paramedian, through a medial minilaminectomy; then, in the same surgical time, the electrode was connected to a programmable pulse generator. All patients have had at least one bypass surgery. One patient was carrier of coronary X syndrome; the other two men had severe angina pain.

Results: At long term follow up, an improvement in NYHA-FC (3,5 to 2,2) and VAS scores was noted. There were no complications and clinical examinations clearly showed an improvement in quality of life and in carrying out physical activity, improvement of the ST segment in ECG, a significant decrease in intake of nitrates and reduction in time and frequency of periods of hospitalization.

Conclusions: Although small, this study demonstrates the beneficial effect of EM in chronic refractory angina. This procedure is considered as additional treatment of first choice for these pa- tients by the European Society of Cardiology and y the American College of Cardiology/American Heart Association Task Force assigned a level of evidence Class IIB.

Metrics

Metrics Loading ...

References

Mannheimer C, Camici P, Chester MR, Collins A, DeJongste M, Eliasson T, et al. The problem of chronic refractory angina; report from the ESC Joint Study Group on the Treatment of Refractory Angina. Eur Heart J. 2002;23(5):355-70.

The Criteria Committee of the New York Heart Association. Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels. 9th ed. Boston, Mass: Little, Brown & Co; 1994. p. 253-6.

Campeau L. Letter: Grading of angina pectoris. Circulation. 1976;54(3):522-3.

Foreman RD. Mechanisms of cardiac pain. Annu Rev Physiol. 1999;61:143-67.

Foreman RD, Qin C. Neuromodulation of cardiac pain and cerebral vasculature: neural mechanisms. Cleve Clin J Med. 2009;76 Suppl 2:S75-9.

Rosen SD, Paulesu E, Frith CD, Frackowiak RS, Davies GJ, Jones T, et al. Central nervous pathways mediating angina pectoris. Lancet. 1994;344(8916):147-50.

Droste C. [Pain perception and peripheral pain localization in angina pectoris] [Article in German] Z Kardiol. 1988;77 Suppl 5:15-33. Erratum in: Z Kardiol 1989;78(3):211.

Melzack R, Wall PD. Pain mechanisms: a new theory. Science. 1965;150(699):971-9.

Hautvast RW, Blanksma PK, DeJongste MJ, Pruim J, van der Wall EE, Vaalburg W, et al. Effect of spinal cord stimulation on myocardial blood flow assessed by positron emission tomography in patients with refractory angina pectoris. Am J Cardiol. 1996;77(7):462-7.

Oosterga M, ten Vaarwerk IA, DeJongste MJ, Staal MJ. Spinal cord stimulation in refractory angina pectoris clinical results and mechanisms. Z Kardiol. 1997;86 Suppl 1:107-13.

Chandler MJ, Brennan TJ, Garrison DW, Kim KS, Schwartz PJ, Foreman RD. A mechanism of cardiac pain suppression by spinal cord stimulation: implications for patients with angina pectoris. Eur Heart J. 1993;14(1):96-105.

Foreman RD, Linderoth B, Ardell JL, Barron KW, Chandler MJ, Hull SS Jr, et al. Modulation of intrinsic cardiac neurons by spinal cord stimulation: implications for its therapeutic use in angina pectoris. Cardiovasc Res. 2000;47(2):367-75.

Droste C. Influence of opiate systems in pain transmission during angina pectoris. Z Kardiol. 1990;79 Suppl 3:31-43.

Svorkdal N. Treatment of inoperable coronary disease and refractory angina: spinal stimulators, epidurals, gene therapy, transmyocardial laser, and counterpulsation. Semin Cardiothorac Vasc Anesth. 2004;8(1):43-58.

Keefer CS, Resnick WH. Angina pectoris: a syndrome caused by anoxemia of the myocardium. Arch Int Med. 1928;41:769.

Murphy DF, Giles KE. Dorsal column stimulation for pain relief from intractable angina pectoris. Pain. 1987;28(3):365-8.

ten Vaarwerk IA, Staal MJ. Spinal cord stimulation in chronic pain syndromes. Spinal Cord. 1998;36(10):671-82.

Ekre O, Norrsell H, Währborg P, Eliasson T, Mannheimer C. Temporary cessation of spinal cord stimulation in angina pectoris-effects on symptoms and evaluation of long-term effect determinants. Coron Artery Dis. 2003;14(4):323-7.

Sanderson JE, Ibrahim B, Waterhouse D, Palmer RB. Spinal electrical stimulation for intractable angina long-term clinical outcome and safety. Eur Heart J. 1994;15(6):810-4.

De Jongste MJ, Nagelkerke D, Hooyschuur CM, Journée HL, Meyler PW, Staal MJ, et al. Stimulation characteristics, complications, and efficacy of spinal cord stimulation systems in patients with refractory angina: a prospective feasibility study. Pacing Clin Electrophysiol. 1994;17(11 Pt 1):1751-60.

Andréll P, Ekre O, Eliasson T, Blomstrand C, Börjesson M, Nilsson M, et al. Cost-effectiveness of spinal cord stimulation versus coronary artery bypass grafting in patients with severe angina pectoris-long-term results from the ESBY study. Cardiology. 2003;99(1):20-4.

Kumar K, Buchser E, Linderoth B, Meglio M, Van Buyten JP. Avoiding complications from spinal cord stimulation: Pactical recommendations from an international panel of experts. Neuromodulation. 2007;10(1):24-33.

Bagger JP, Jensen BS, Johannsen G. Long-term outcome of spinal cord electrical stimulation in patients with refractory chest pain. Clin Cardiol. 1998;21(4):286-8.

De Vries J, De Jongste MJ, Spincemaille G, Staal MJ. Spinal cord stimulation for ischemic heart disease and peripheral vascular disease. Adv Tech Stand Neurosurg. 2007;32:63-89.

De Jongste MJ, Haaksma J, Hautvast RW, Hillege HL, Meyler PW, Staal MJ, et al. Effects of spinal cord stimulation on myocardial ischaemia during daily life in patients with severe coronary artery disease. A prospective ambulatory electrocardiographic study. Br Heart J. 1994;71(5):413-8.

Mannheimer C, Eliasson T, Andersson B, Bergh CH, Augustinsson LE, Emanuelsson H, et al. Effects of spinal cord stimulation in angina pectoris induced by pacing and possible mechanisms of action. BMJ. 1993;307(6902):477-80.

Andersen C, Hole P, Oxhøj H. Does pain relief with spinal cord stimulation for angina conceal myocardial infarction? Br Heart J. 1994;71(5):419-21.

Chauhan A, De Jongste MJ. Neurostimulation and myocardial ischaemia. Br Heart J. 1994;72(6):595.

Eliasson T, Jern S, Augustinsson LE, Mannheimer C. Safety aspects of spinal cord stimulation in severe angina pectoris. Coron Artery Dis. 1994;5(10):845-50.

Mannheimer C, Augustinsson LE, Eliasson T. [Spinal cord stimulation in severe angina pectoris. Reduced ischemia and increased quality of life] [Article in Swedish] Lakartidningen. 1994;91(37):3257-61.

Diedrichs H, Weber M, Voth E, Koulousakis A, Zobel C, Schwinger RH. [Increased myocardial blood flow after spinal cord stimulation in patients with refractory angina pectoris] [Article in German] Med Klin (Munich). 2003;98(3):146-50.

Mannheimer C, Eliasson T, Augustinsson LE, Blomstrand C, Emanuelsson H, Larsson S, et al. Electrical stimulation versus coronary artery bypass surgery in severe angina pectoris: the ESBY study. Circulation. 1998;97(12):1157-63.

Norrsell H, Pilhall M, Eliasson T, Mannheimer C. Effects of spinal cord stimulation and coronary artery bypass grafting on myocardial ischemia and heart rate variability: further results from the ESBY study. Cardiology. 2000;94(1):12-8.

Ekre O, Eliasson T, Norrsell H, Währborg P, Mannheimer C; Electrical Stimulation versus Coronary Artery Bypass Surgery in Severe Angina Pectoris. Long-term effects of spinal cord stimulation and coronary artery bypass grafting on quality of life and survival in the ESBY study. Eur Heart J. 2002;23(24):1938-45.

Greco S, Auriti A, Fiume D, Gazzeri G, Gentilucci G, Antonini L, Santini M. Spinal cord stimulation for the treatment of refractory angina pectoris: a two-year follow-up. Pacing Clin Electrophysiol. 1999;22(1 Pt 1):26-32.

Murray S, Carson KGS, Collins PD, James MA. Spinal cord stimulation significantly reduces hospital readmissions in patients with intractable angina pectoris. Heart. 1998;79(suppl):48.

Yu W, Maru F, Edner M, Hellström K, Kahan T, Persson H. Spinal cord stimulation for refractory angina pectoris: a retrospective analysis of ef- ficacy and cost-benefit. Coron Artery Dis. 2004;15(1):31-7.

Kumar K, Wilson JR, Taylor RS, Gupta S. Complications of spinal cord stimulation, suggestions to improve outcome, and financial impact. J Neurosurg Spine. 2006;5(3):191-203.

Yang EH, Barsness GW, Gersh BJ, Chandrasekaran K, Lerman A. Current and future treatment strategies for refractory angina. Mayo Clin Proc. 2004;79(10):1284-92.

Deer TR, Stewart CD. Complications of Spinal Cord Stimulation: Identification, Treatment, and Prevention. Pain Med. 2008;9(S1):S93-S101.

Satran D, Traverse JH, Barsness GW, Lerman A, Simari RD, Poulose AK, et al. Emerging therapies for refractory angina. Minn Med. 2008;91(1):36-9.

DeJongste MJ, Tio RA, Foreman RD. Chronic therapeutically refractory angina pectoris. Heart. 2004;90(2):225-30.

Stella OA, Morello F, Condolí Alcorta S.et al. Neuromodulación quirúrgica eléctrica y dolor. Revisión y estado actual. Arch.Neurol.Neuroc. Neuropsiquiatr.2008;15 (2)34-44.

Singh H, Merry AF, Ruygrok P, Ruttley A. Treatment of recurrent chest pain in a heart transplant recipient using spinal cord stimulation. Anaesth Intensive Care. 2008;36(2):242-4.

Lapenna E, Rapati D, Cardano P, De Bonis M, Lullo F, Zangrillo A, Alfieri O. Spinal cord stimulation for patients with refractory angina and previous coronary surgery. Ann Thorac Surg. 2006;82(5):1704-8.

Eckert S, Horstkotte D. Management of angina pectoris: the role of spinal cord stimulation. Am J Cardiovasc Drugs. 2009;9(1):17-28.

Börjesson M, Andrell P, Lundberg D, Mannheimer C. Spinal cord stimula- tion in severe angina pectoris a systematic review based on the Swedish Council on Technology assessment in health care report on long-standing pain. Pain. 2008;140(3):501-8.

Fraker TD Jr, Fihn SD; 2002 Chronic Stable Angina Writing Committee; American College of Cardiology; American Heart Association, Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS, et al. 2007 chronic angina focused update of the ACC/AHA 2002 guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 guidelines for the management of patients with chronic stable angina. J Am Coll Cardiol. 2007;50(23):2264-74. Erratum in: J Am Coll Cardiol. 2007;50(23):e1. Pasternak, Richard C [removed].

Published

2009-11-01

How to Cite

1.
Stella OA. Spinal cord stimulation for angina pectoris: Remote observations. NeuroTarget [Internet]. 2009 Nov. 1 [cited 2024 Nov. 22];4(3):25-31. Available from: https://neurotarget.com/index.php/nt/article/view/316

Issue

Section

Original