Uso del fentanilo transdérmico para la analgesia postoperatoria en cirugía de artrodesis del raquis: Publicado en la Revista Dor. São Paulo, 2011;12(2):115-9

José Nilson Fortaleza de Araújo; Samantha Ottoni Adolphsson Zidan; Rute Maria Araújo Cavalcante; Roberto Cesar Ponte Ibiapina

doi:10.47924/neurotarget2013269

Authors

José Nilson Fortaleza de Araújo Anesthesiologist at the Doctor José Frota Institute. Fortress, CE, Brazil
Samantha Ottoni Adolphsson Zidan Resident Anesthesiologist at the Doctor José Frota Institute. Fortaleza, CE, Brazil.
Rute Maria Araújo Cavalcante Resident Anesthesiologist at the Doctor José Frota Institute. Fortaleza, CE, Brazil.
Roberto Cesar Ponte Ibiapina Anesthesiologist at the Doctor José Frota Institute. Fortress, CE, Brazil

DOI:

https://doi.org/10.47924/neurotarget2013269

Keywords:

Analgesia, Arthrodesis, Fentanyl, Percutaneous adhesive, Spine

Abstract

Background and Objectives: Moderate to severe postoperative pain control is still a daily problem due to pain in the intervals between analgesic administration and to adverse effects. Percutaneous fentanyl induces continuous analgesia for up to 72 hours and has been used to control acute pain. This study aimed at evaluating percutaneous fentanyl analgesia to control acute postoperative pain in patients submitted to spinal arthrodesis, as well as at observing the incidence of fentanyl-related adverse effects.
Method: Participated in this study 9 patients submitted to spinal arthrodesis under general anesthesia with propofol, sufentanil and cisatracurium and maintenance with remifentanil and isoflurane. One 12 μg/h percutaneous fentanyl adhesive was applied before surgery and ketoprofen, dipirone and tramadol were administered at surgery completion. Dipirone was administered every 6 hours as rescue analgesic drug. Pain intensity was evaluated every 12 hours by the visual analog scale and dipirone and ketoprofen consumption was evaluated every 12-hours; adverse effects were recorded
Results: Twelve hours after adhesive application, mean pain intensity was 2.11 ± 2.84. Highest pain intensity was observed 60 hours after adhesive application and lowest value was observed 24 and 72 hours after percutaneous fentanyl adhesive application. Highest total dipirone consumption was 8000 mg in the period between 60 and 72 hours and between 36 and 48 hours and the lowest consumption was zero mg in the period between 60 and 72 hours, but there has been no statistically significant difference in observed periods (p = 0.47). Side effects were one case of sleepiness and one of nausea and vomiting.
Conclusion: This study suggests that percutaneous fentanyl is safe and effective for postoperative spinal surgery pain. Results have also shown that percutaneous fentanyl has minor side effects.

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