Factores pronóstico en pacientes a quienes se les realizó lesión por radiofrecuencia de las radiaciones prelemniscales, para el tratamiento de los síntomas motores de la enfermedad de Parkinson

José Luis Navarro Olvera

doi:10.47924/neurotarget2015242

Authors

José Luis Navarro Olvera Functional Neurosurgery, Stereotaxy and Radiosurgery Service of the General Hospital of Mexico. Mexico DF.

DOI:

https://doi.org/10.47924/neurotarget2015242

Keywords:

Parkinson´s Disease, lesion, prelemniscal radiation

Abstract

Introduction. Prelemniscal radiations (RAPRL) are a frequently used target for ablation or stimulation for the treatment of motor symptoms from Parkinson’s disease like tremor or rigidity.
The stereotactic location is 2.5 to 5 mm in front of the PC,11 to 13 lateral to the midline and 2.5 to 5 mm below the AC-PC line.
Methods. We analysed 34 cases of radiofrequency ablation in the RAPRL from 2006 to 2012 in the Hospital General de Mexico, with a follow up of 2 years, identifying prognostic factors. For statistics we used Student’s T test and the Pearson test.
Results. We found important statistical significance in favorable prognostic factors such as age <55 years at the time of surgery and Hoehn and Yahr scale less than III at the moment of surgery. There was no statistical significance for variables like time with the disease, levodopa dose before surgery, degrees Celsius applied for the lesion and seconds of it’s duration.
Conclusions. The prognosis after lesion of the prelemniscal radiations for Parkinson’s disease is better for those patients that at the moment of surgey have an age less or equal than 55 years and a Hoehn and Yahr scale lower than III.

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