Comparación de la terapia de ultrasonido continuo y pulsado en la  hiperalgesia de rodilla en ratas Wistar.: Publicado originalmente en la Revista Dor. São Paulo, 2014 oct-dic;15(4):287-9

Gladson Ricardo Flor Bertolini; Josinéia Gresele Coradini; Regina Inês Kunz; Bruno Pogorzelski Rocha; Lígia Inez da Silva

doi:10.47924/neurotarget2016173

Authors

Gladson Ricardo Flor Bertolini Universidad de São Paulo, Escuela de Medicina de Ribeirão Preto, Ribeirão Preto, SP, Brasil.
Josinéia Gresele Coradini Universidad Estatal de Oeste de Paraná, Departamento de Fisioterapia, Cascavel, PR, Brasil.
Regina Inês Kunz Universidad Estatal de Oeste de Paraná, Departamento de Fisioterapia, Cascavel, PR, Brasil.
Bruno Pogorzelski Rocha Universidad Estatal de Oeste de Paraná, Departamento de Fisioterapia, Cascavel, PR, Brasil.
Lígia Inez da Silva Universidad Federal de Paraná, Departamento de Fisioterapia, Curitiba, PR, Brasil.

DOI:

https://doi.org/10.47924/neurotarget2016173

Keywords:

Edema, Pain measurement, Ultrasound therapy

Abstract

Backgrounds and Objectives: Among electro agents ultrasound is one of the most common, however, there is insufficient evidence of the beneficial effects with the parameters currently used. The aim of this study was to compare the effect of continuous and pulsed ultrasound therapy on experimental hyperalgesia and edema in knees of Wistar rats.
Methods: 18 rats were divided into three groups: CG- control group; GUP - treated with pulsed ultrasound 50%; and GUC - continuous ultrasound. To accomplish the lesion, animals were manually restrained and 100μL of 5% formalin solution were injected into the right tibiofemoral space. For assessment of nociception digital Von Frey filament was used on the medial side of the joint, until clinching. Edema was evaluated with mid-lateral knee caliper. Assessments occurred in the preinjury
(EV1), after 15 (EV2), 30 (EV3) and 60 (EV4) minutes of the injury. After EV2, treatment was initiated with ultrasound with 0.4W/cm2 (SATA), pulsed or continuous.
Results: The CG had hypernociception, with no return to baseline. GUP has returned to baseline as from EV3 and for continuous ultrasound in EV4. All three groups showed similar behavior for edema, with onset in EV2, without reduction.
Conclusion: Therapeutic ultrasound was effective to decrease nociception, and the pulsed form showed early results, however, both forms of application had no effect on the formation and maintenance of acute edema.

Metrics

Metrics Loading ...

References

Warden SJ. A new direction for ultrasound therapy in sports medicine. Sports Med.2003;33(2):95-107.

Wong RA, Schumann B, Townsend R, Phelps CA. A survey of therapeutic ultrasound use by physical therapists who are orthopaedic certified specialists. Phys Ther. 2007;87(8):986-94.

Martignano CC, Silva LI, Meireles A, Rocha BP, Rosa CT, Bertolini GR. Avaliação do ultrassom sobre a hiperalgesia e o edema em joelhos de rato Wistar e interferências de um inibidor de opioides endógenos. Fisioter Bras. 2013;14(4):289-93.

Yildirim MA, Ones K, Celik EC. Comparison of ultrasound therapy of various durations in the treatment of subacromial impingement syndrome. J Phys Ther Sci. 2013;25(9):1151-4.

Alexander LD, Gilman DR, Brown DR, Brown JL, Houghton PE. Exposure to low amounts of ultrasound energy does not improve soft tissue shoulder pathology: a systematic review. Phys Ther. 2010;90(1):14-25.

Van den Bekerom MP, van der Windt DA, Ter Riet G, van der Heijden GJ, Bouter LM. Therapeutic ultrasound for acute ankle sprains. Eur J Phys Rehabil Med. 2012;48(2):325-34.

Fiore P, Panza F, Cassatella G, Russo A, Frisardi V, Solfrizzi V, et al. Shortterm effects of high-intensity laser therapy versus ultrasound therapy in the treatment of low back pain: a randomized controlled trial. Eur J Phys Rehabil Med. 2011;47(3):367-73.

Licciardone JC, Minotti DE, Gatchel RJ, Kearns CM, Singh KP. Osteopathic manual treatment and ultrasound therapy for chronic low back pain: a randomized controlled trial. Ann Fam Med. 2013;11(2):122-9.

Luksurapan W, Boonhong J. Effects of phonophoresis of piroxicam and ultrasound on symptomatic knee osteoarthritis. Arch Phys Med Rehabil. 2013;94(2):250-5.

Ciena AP, Cunha NB, Moesch J, Mallmann JS, Carvalho AR, Moura PJ de, et al. Efeitos do ultrassom terapêutico em modelo experimental de ciatalgia. Rev Bras Med Esporte. 2009;15(6):424-7.

Martins MA, de Castro Bastos L, Tonussi CR. Formalin injection into knee joints of rats: pharmacologic characterization of a deep somatic nociceptive model. J Pain. 2006;7(2):100-7.

Vivancos GG, Verri WA Jr, Cunha TM, Schivo IR, Parada CA, Cunha FQ, et al. An electronic pressure-meter nociception paw test for rats. Braz J Med Biol Res. 2004;37(3):391-9.

Gould D, Yousaf N, Fatah R, Subang MC, Chernajovsky Y. Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental arthritis. Arthritis Res Ther. 2007;9(1):R7.

Bertolini GR, Silva TS, Ciena AP, Artifon EL. Comparação do ultrassom pulsado e contínuo no reparo tendíneo de ratos. Fisioter Pesq. 2012;19(3):242-7.

Coradini JG, Mattjie TF, Bernardino GR, Peretti AL, Kakihata CM, Errero TK, et al. [Comparison of low level laser, ultrasonic therapy and association in joint pain in Wistar rats]. Rev Bras Reumatol. 2013;54(1):7-12. English, Portuguese.