Subtalamotomía y palidotomía simultáneas en un caso de temblor parkinsoniano severo.

Boris Zurita Cueva; Fidel Villamar Zambrano; Jorge Altamirano; Andrés Peña Gaybor; Lorena Desiderio Rodrigo

doi:10.47924/neurotarget2017138

Autores/as

Boris Zurita Cueva Departamento de Neurocirugía. Omni Hospital. Guayaquil, Ecuador.
Fidel Villamar Zambrano Omni Hospital. Guayaquil, Ecuador.
Jorge Altamirano Omni Hospital. Guayaquil, Ecuador.
Andrés Peña Gaybor Omni Hospital. Guayaquil, Ecuador.
Lorena Desiderio Rodrigo Omni Hospital. Guayaquil, Ecuador.

DOI:

https://doi.org/10.47924/neurotarget2017138

Palabras clave:

Enfermedad de Parkinson, Globo Pálido Interno, Palidotomía, Subtalamotomía, Temblor

Resumen

Se describe el caso de un paciente con hemiparkinson con predominio de temblor.
El paciente fue sometido a tratamiento con radiofrecuencia estereotáxica a nivel de zona incerta caudal (ZI), con resultado regular; en la misma intervención, se decidió realizar una lesión adicional en el globo pálido interno, cediendo totalmente el temblor. Se describe la técnica quirúrgica utilizada y se discute el papel del globo pálido interno (Gpi) en el temblor parkinsoniano.

Métricas

Cargando métricas ...

Citas

Bertrand G, Jasper H.: Microelectrode recording of unit activity in the human thalamus. Confin Neurol 1965; 26: 205-8.

Bertrand C, Molina Negro P, Martinez N, Velasco F. Stereotaxic Surgery in Parkinson´s Disease. Progress in Neurological Surgery. Krayenbuhl H, Maspes P, Sweet W. Eds. Year Book Medical Publishers Vol. V, 1974.

Plaha P, Ben Schlomo Y, Patel NK, Gill SS. Stimulation in caudal zona incerta is superior to stimulation of subthalamic nucleus in improving contralateral parkinsonism. Brain 2006; 129:1732-47.

Plaha P, Filipovic S, Gill SS. Induction of Parkinsonian resting tremor by stimulation of caudal zona incerta nucleus. A clinical study. J Neurol Neurosurg Psychiatry. 2008; 79: 514-21.

Bendersky D, Ajler P, Yampolsky C. El uso de la neuromodulación para el tratamiento del temblor. Surg Neurol Int 2014; 5: S 232-46.

Zurita-Cueva B, Villamar F, Cornejo P, Bedoya C, Altamirano J. Haz Prerrúbrico de Papéz y zona incerta caudal en la enfermedad de Parkinson. Neurotarget 2009; Vol 4 (3):41-50.

Zurita-Cueva B, Villamar F, Guerrero P, Bedoya C, Cornejo P. Pálido-Ansotomía Lenticular: Un blanco quirúrgico efectivo en la enfermedad de Parkinson. Rev Ecuat Neurol 2007; 16(3):237-41.

Obeso JA, Jahanshahi M, Alvarez L, Macias R, Pedroso I, Wilkinson L, Pavon N, Day B, Pinto S, Rodriguez –Oroz MC,

Tejeiro J, Artieda J, Talelli P, Swayne O, Rodriguez Bathia K, Rodriguez –Diaz M, Lopez G, Guridi J, Rothwell JC. What can man do without basal ganglia motor output? The effect of combined unilateral subthalamotomy and pallidotomy in a patient with Parkinson´s disease. Exp Neurol 2009; Dec 220(2):283-92.

Peppe A, Pierantozi M, Bassi A, Altibrandi MG, Brusa L, Stanzione P, Mazzone P. Stimulation of Subthalamic Nucleus compared with the Globus Pallidus Internus in patients with Parkinson Disease. J Neurosurg 2004 August; 101(2):195-200.

Goto S, Yamada K. Combination of thalamic Vim stimulation and Gpi pallidotomy synergistically abolishes Holme´s tremor. J Neurol Neurosurg Psychiatry 2004; 75:1200-7.

Llumiguano C, Dóczi T, Baths I. Tratamiento de la enfermedad de Parkinson con palidotomía y palidotalamotomía estereotáctica guiada por microelectrodos. Neurocirugía 2006; 17: 420-32.

Hutchinson WD, Lozano AM, Tasker RR, Lang AE, Dostrovsy JO. Identification and characterization of neurons with tremorfrequency activity in human globus pallidus. Exp Brain Res 1997; 113(3):557-63.

Rodriguez-Oroz M, Rodriguez M, Guridi J, Mewes K, Chockkman V, Vitek J, Delong MR, Obeso JA. The subthalamic nucleus in Parkinson´s disease: Somatotopic organization and phisiological characteristics. Brain 2001; 124:1777-90.

Guridi J, Gorospe A, Ramos E, Linazasoro G, Rodriguez MC, Obeso JA. Stereotactic targeting of the globus pallidus internus in Parkinson´s Disease: Imaging versus electrophysiological Mapping. Neurosurg 1999; 45: 278-89.

Gross R, Lombardi WJ, Lang AE, Duff J, Hutchinson WD, Saint –Cyr JA, Tasker RR, Lozano AM. Relationship of lesion location to clinical outcome following microelectrode- guided pallidotomy for Parkinson´s Disease. Brain 1999; 122: 405-16.

Eskandar EN, Cosgrove RG, Shinobu NA, Penney JB. The importance of accurate lesion placement in posteroventral pallidotomy. Report of two cases. J Neurosurg 1998; 89:630-4.

Kishore A, Panikar D, Balakrishnan S, Joseph F, Sarma S. Evidence of functional somatotopy in GPi from results of pallidotomy. Brain 2000; 123:2491-500.

Dun RP, Strict PL. The basal ganglia communicate with the cerebellum. PNAS 2010 May 4; 107, n°18:8452-6

Dovzhenok A, Rubchinsky LL. Modeling the origin of parkinsonian tremor. BMC Neuroscience 2010; 11(suppl):34.

Bostan AC, Strict PL. The Cerebellum and Basal Ganglia are interconnected. Neuropsychol Rev. 2010 September 20(3); 261-70.

Hoshi E, Tremblay L, Féger J, Carras PL, Strick PL. The cerebellum communicates with the basal ganglia. Nature Neuroscience 2005; Vol 8, N-11:1491-3.

Helmich RC, Jansen MJR, Oyen WJG, Bloem BR, Toni I. Pallidal dysfunction drives a cerebellothalamic circuit into Parkinson tremor. Ann Neurol 2011;Feb . 69 (2):269-81.

Kobayashi K, Katayama Y, Kasai M, Oshima H, Fukaya C, Yamamoto T. Localization of thalamic cells with tremor –frequency activity in Parkinson´s disease and essential tremor. Acta Neurochir suppl 2003; 87:137-9

Benpazi H, Bergman H, Goldberg JA, Giladi N, Hansel D, Reches A, Simon ES. Synchrony of rest tremor in multiple limbs in Parkinson´s disease: Evidence of multiples oscilators. J Neural Transm (2001) 108:287-96.

Hurtado JM, Rubchinsky LL, Sigvardt KA, Wheellock VL, Pappas CT. Temporal evolutions of oscillations and Synchrony of Gpi/muscle Pairs in Parkinson´s Disease. JNeurophisiol 2005; 93:1569-84.

Hurtado JM, Gray CM, Tamas LB, Sigbart KA. Dynamics of tremor- related oscillations in the human globus pallidus: A single case study. Proc Natl Acad Sci USA 1999; 96:1674-9

Lozano AM, Tasker RR, Lang AE, Dostrovsky AO. Identification and Characterization of neurons with tremor frequency activity in human globus pallidus. Exp Brain Res 1997; 113: 557-563.

Goto S, Nishikawa S, Mita S, Ushio Y, Impact of posterior Gpi pallidotomy on leg tremor in Parkinson´s disease. Stereotact Funct Neurosurg 2002; 78:64-9

Lozano AM, Lang AE, Hutchingson WD. Pallidotomy for tremor. Movement disorders 1998; 13(53):107-11.

Miyagi Y, Shima S, Ishido K, et al. Posteroventral Pallidotomy for midbrain tremor after pontine hemorrhage. J Neurosurg 1999; 91:885-8.

Taha JM, Favre J, Baumann TK, Burchiel KJ. Tremor control after Pallidotomy in patients with Parkinson´s disease. Correlation with microrecordings findings. J Neurosurg 1997; April 86(4):642-7.