Una actualización sobre estimulación cerebral profunda para el tratamiento de enfermedades psiquiátricas
DOI:
https://doi.org/10.47924/neurotarget2006436Palabras clave:
estimulación cerebral profunda, depresión, trastorno obsesivo compulsivo, Síndrome de TouretteResumen
En 2006, el mundo científico celebró el 70º aniversario de la publicación del primer artículo científico del Dr. Moniz sobre los resultados de pequeñas series de pacientes leucotomizados, un acontecimiento que marcó el nacimiento de la neurocirugía psiquiátrica moderna. En las últimas décadas, este campo de la neurocirugía funcional ha sido testigo de una gran popularidad, una desaparición casi completa y, recientemente, un resurgimiento del interés respaldado por los avances en la cirugía y las imágenes. En este artículo, revisamos la literatura actual y la experiencia clínica en un intento de proporcionar una visión general y actualizada sobre el uso de la estimulación cerebral profunda en el tratamiento del trastorno obsesivo compulsivo y otras afecciones psiquiátricas médicamente intratables. Se realizó una búsqueda detallada de la literatura científica actual sobre temas de cirugía psiquiátrica y estimulación cerebral profunda (ECP). Luego se revisó críticamente la información obtenida. La revisión indica que existe un creciente cuerpo de literatura que documenta el tratamiento exitoso de ciertas condiciones psiquiátricas con DBS. Las imágenes fisiológicas y metabólicas modernas parecen ser útiles para elegir objetivos quirúrgicos apropiados. Según esta revisión, parece que la ECP está ganando popularidad en el tratamiento de trastornos psiquiátricos médicamente intratables y se puede esperar un crecimiento significativo en futuras investigaciones y aplicaciones clínicas de la ECP para indicaciones psiquiátricas.
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