An update on deep brain stimulation for treatment of psychiatric conditions
DOI:
https://doi.org/10.47924/neurotarget2006436Keywords:
deep brain stimulation (DBS), depression, obsessive-compulsive disorder, Tourette syndromeAbstract
In 2006, the scientific world celebrated 70th anniversary of publication of the first scientific paper by Dr. Moniz on results of small series of leucotomy patients – an event that marked birth of the modern psychiatric neurosurgery. Over the last few decades, this field of functional neurosurgery witnessed widespread popularity, almost complete disappearance, and, recently, resurgence of interest supported by the progress in surgery and imaging.
In this paper, we review current literature and clinical experience in attempt to provide an overview and update on the use of deep brain stimulation in the treatment of the obsessive compulsive disorder and other medically intractable psychiatric conditions. Detailed search of current scientific literature was performed on topics of psychiatric surgery and deep brain stimulation (DBS). The information obtained was then critically reviewed.
Review indicates that there is a growing body of literature documenting successful treatment of certain psychiatric conditions with DBS. Modern physiological and metabolic imaging appears to be useful in choosing appropriate surgical targets. Based on this review, it appears that DBS is gaining popularity in the treatment of medically intractable psychiatric disorders and one may expect significant growth in further research and clinical applications of DBS for psychiatric indications.
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References
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