Haz prerrúbrico de Papez y zona incierta caudal en la enfermedad de Parkinson
DOI:
https://doi.org/10.47924/neurotarget2009320Palabras clave:
zona incierta, núcleo ventral intermedio medial, Vim, campo prerrúbrico de Forel, subtalamotomía, temblorResumen
Diez pacientes con la enfermedad de Parkinson avanzada fueron sometidos a subtalamotomía por radiofrecuencia a nivel de la parte caudal de la zona incierta y el campo prerrúbrico de Forel, justo por debajo del núcleo ventral intermedio medial (Vim) en su porción externa. Los pacientes fueron evaluados en el estado en “ON” con las escalas UPDRS III, Hoehn-Yahr y Schwab-England antes y hasta un año después de la cirugía. Se logró una mejoría del temblor en un 80% en promedio en todos los pacientes. No hubo complicaciones. Los autores concluyen que la lesión por radiofrecuencia en esa región es un método seguro y efectivo para tratar a los pacientes parkinsonianos en etapas avanzadas de la enfermedad.
Métricas
Citas
Ward AA Jr, McCulloch WS, Magoun HW. Production of an alternating tremor at rest in monkeys. J Neurophysiol. 1948 Jul;11(4):317-30.
Goldstein M, Battista AF, Nakatani S, Anagnoste B. The effects of centrally acting drugs on tremor in monkeys with mesencephalic lesions. Proc Natl Acad Sci U S A. 1969 Aug;63(4):1113-6.
Santens P, Boon P, Van Roost D, Caemaert J. The pathophysiology of motor symptoms in Parkinson’s disease. Acta Neurol Belg. 2003 Sep;103(3):129- 34.
Cavdar S, Onat F, Cakmak YO, Saka E, Yananli HR, Aker R. Connections of the zona incerta to the reticular nucleus of the thalamus in the rat. J Anat. 2006 Aug;209(2):251-8.
Zurita-Cueva B, Villamar F, Guerrero P, Bedoya C, Cornejo P, Navarrete M. Pálido-ansotomía lenticular: Un blanco quirúrgico efectivo en la enferme- dad de Parkinson. Rev Ecuat Neurol. 2007;16(3):237-41.
Spiegelmann R, Friedman WA. Rapid determination of thalamic CT stereotactic coordinates: a method. Acta Neurochir (Wien). 1991;110(1- 2):77-81.
Paré D, Curro’Dossi R, Steriade M. Neuronal basis of the parkinsonian resting tremor: a hypothesis and its implications for treatment. Neuroscience. 1990;35(2):217-26.
Deiber MP, Pollak P, Passingham R, Landais P, Gervason C, Cinotti L, Friston K, Frackowiak R, Mauguière F, Benabid AL. Thalamic stimulation and suppression of parkinsonian tremor. Evidence of a cerebellar deactivation using positron emission tomography. Brain. 1993 Feb;116 ( Pt 1):267-79.
Deuschl G, Wilms H, Krack P, Würker M, Heiss WD. Function of the cerebellum in Parkinsonian rest tremor and Holmes’ tremor. Ann Neurol. 1999 Jul;46(1):126-8.
Kassubek J, Juengling FD, Hellwig B, Knauff M, Spreer J, Lücking CH. Hypermetabolism in the ventrolateral thalamus in unilateral Parkinsonian resting tremor: a positron emission tomography study. Neurosci Lett. 2001 May 18;304(1-2):17-20.
Benazzouz A, Tai CH, Meissner W, Bioulac B, Bezard E, Gross C. High-frequency stimulation of both zona incerta and subthalamic nucleus induces a similar normalization of basal ganglia metabolic activity in experimental parkinsonism. FASEB J. 2004 Mar;18(3):528-30.
Plaha P, Khan S, Gill SS. Bilateral stimulation of the caudal zona incerta nucleus for tremor control. J Neurol Neurosurg Psychiatry. 2008 May;79(5):504-13.
Plaha P, Ben-Shlomo Y, Patel NK, Gill SS. Stimulation of the caudal zona incerta is superior to stimulation of the subthalamic nucleus in improving contralateral parkinsonism. Brain. 2006 Jul;129(Pt 7):1732-47.
Périer C, Tremblay L, Féger J, Hirsch EC. Behavioral consequences of biculline injection in the subthalamic nucleus and the zona incerta in rat. J Neurosci. 2002 Oct 1;22(19):8711-9.
Masri R, Trageser JC, Bezdudnaya T, Li Y, Keller A. Cholinergic regulation of the posterior medial thalamic nucleus. J Neurophysiol. 2006 Nov;96(5):2265-73.
Plaha P, Patel NK, Gill SS. Stimulation of the subthalamic region for essential tremor. J Neurosurg. 2004 Jul;101(1):48-54.
Plaha P, Filipovic S, Gill SS. Induction of parkinsonian resting tremor by stimulation of the caudal zona incerta nucleus: a clinical study. J Neurol Neurosurg Psychiatry. 2008 May;79(5):514-21.
Brodkey JA, Tasker RR, Hamani C, McAndrews MP, Dostrovsky JO, Lozano AM. Tremor cells in the human thalamus: differences among neurological disorders. J Neurosurg. 2004 Jul;101(1):43-7.
Lenz FA, Tasker RR, Kwan HC, Schnider S, Kwong R, Murayama Y, et al. Single unit analysis of the human ventral thalamic nuclear group: correlation of thalamic “tremor cells” with the 3-6 Hz component of parkinsonian tremor. J Neurosci. 1988 Mar;8(3):754-64.
Jahnsen H, Llinás R. Ionic basis for the electro-responsiveness and oscillatory properties of guineapig thalamic neurones in vitro. J Physiol. 1984 Apr;349:227-47.
Bertolino M, Llinás RR. The central role of voltage-activated and receptor- operated calcium channels in neuronal cells. Annu Rev Pharmacol Toxicol. 1992;32:399-421.
Jeanmonod D, Magnin M, Morel A. Low-threshold calcium spike bursts in the human thalamus. Common physiopathology for sensory, motor and limbic positive symptoms. Brain. 1996 Apr;119 (Pt 2):363-75.
Llinás RR, Steriade M. Bursting of thalamic neurons and states of vigilance. J Neurophysiol. 2006 Jun;95(6):3297-308.
Chemin J, Monteil A, Perez-Reyes E, Bourinet E, Nargeot J, Lory P. Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability. J Physiol. 2002 Apr 1;540(Pt 1):3-14.
Sarnthein J, Jeanmonod D. High thalamocortical theta coherence in patients with Parkinson’s disease. J Neurosci. 2007 Jan 3;27(1):124-31.
Farmer S. Neural rhythms in Parkinson’s disease [editorial]. Brain. 2002 Jun;125(Pt 6):1175-6.
Timmermann L, Gross J, Dirks M, Volkmann J, Freund HJ, Schnitzler A. The cerebral oscillatory network of parkinsonian resting tremor. Brain. 2003 Jan;126(Pt 1):199-212.
Foffani G, Priori A, Egidi M, Rampini P, Tamma F, Caputo E, et al. 300-Hz subthalamic oscillations in Parkinson’s disease. Brain. 2003 Oct;126(Pt 10):2153-63.
Foffani G, Bianchi AM, Baselli G, Priori A. Movement-related frequency modulation of beta oscillatory activity in the human subthalamic nucleus. J Physiol. 2005 Oct 15;568(Pt 2):699-711.
Levy R, Ashby P, Hutchison WD, Lang AE, Lozano AM, Dostrovsky JO. Dependence of subthalamic nucleus oscillations on movement and dopamine in Parkinson’s disease. Brain. 2002 Jun;125(Pt 6):1196-209.
Kühn AA, Williams D, Kupsch A, Limousin P, Hariz M, Schneider GH, et al. Event-related beta desynchronization in human subthalamic nucleus correlates with motor performance. Brain. 2004 Apr;127(Pt 4):735-46.
Doder M, Rabiner EA, Turjanski N, Lees AJ, Brooks DJ; 11C-WAY 100635 PET study. Tremor in Parkinson’s disease and serotonergic dysfunction: an 11C-WAY 100635 PET study. Neurology. 2003 Feb 25;60(4):601-5.
Papez JW, Stotler WA. Connections of the red nucleus. Arch Neurol Psychiatry (Chicago). 1940;44:776-91.
De Armond SJ, Fusco MM, Dewey MM. Structure of the human brain: A photographic atlas. 2nd ed. New York: Oxford University Press; 1976.
Talairach J, David M, Tournoux P, Corredor H, Kvasina T. Atlas d’Anatomie Stéréotaxique. Reperage radiologique indirect des noyaux gris centraux des regions mesencephalo-sous-optique et hypothalamique de l’homme [Article in French]. Paris: Masson & Cie; 1957. p. 162-4.
Patel NK, Heywood P, O’Sullivan K, McCarter R, Love S, Gill SS. Unilateral subthalamotomy in the treatment of Parkinson’s disease. Brain. 2003 May;126(Pt 5):1136-45.
Su PC, Tseng HM, Liu HM, Yen RF, Liou HH. Subthalamotomy for advanced Parkinson disease. J Neurosurg. 2002 Sep;97(3):598-606.
Murata J, Kitagawa M, Uesugi H, Saito H, Iwasaki Y, Kikuchi S, et al. Electrical stimulation of the posterior subthalamic area for the treatment of intractable proximal tremor. J Neurosurg. 2003 Oct;99(4):708-15.
Velasco F, Jiménez F, Pérez ML, Carrillo-Ruiz JD, Velasco AL, Ceballos J, et al. Electrical stimulation of the prelemniscal radiation in the treatment of Parkinson’s disease: an old target revised with new techniques. Neurosurgery. 2001 Aug;49(2):293-306; discussion 306-8.
Carrillo-Ruiz JD, Velasco F, Jimènez F, Castro G, Velasco AL, Hernández JA, et al. Bilateral electrical stimulation of prelemniscal radiations in the treatment of advanced Parkinson’s disease. Neurosurgery. 2008 Feb;62(2):347-57.
Velasco FC, Molina-Negro P, Bertrand C, Hardy J. Further definition of the subthalamic target for arrest of tremor. J Neurosurg. 1972 Feb;36(2):184- 91.
Bertrand C, Hardy J, Molina-Negro P, Martinez N. Optimum physiological target for the arrest of tremor. In: Gillingham F, Donaldson I, editors. Third symposium on Parkinson’s disease. Edinburgh: E & S Livingstone; 1969. p. 251-4.
Velasco F, Velasco M. A reticulothalamic system mediating proprioceptive attention and tremor in man. Neurosurgery. 1979 Jan;4(1):30-6.
Velasco F, Velasco M, Machado JP. A statistical outline of the subthalamic target for the arrest of tremor. Appl Neurophysiol 1975;38(1):38-46.
Velasco F, Velasco M, Ogarrio C, Olvera A. Neglect induced by thalamotomy in humans: a quantitative appraisal of the sensory and motor deficits. Neurosurgery. 1986 Nov;19(5):744-51.
Velasco FC, Molina-Negro P, Bertrand C, Hardy J. Further definition of the subthalamic target for arrest of tremor. J Neurosurg. 1972 Feb;36(2):184- 91.
Kim MC, Son BC, Miyagi Y, Kang JK. Vim thalamotomy for Holmes’ tremor secondary to midbrain tumour. J Neurol Neurosurg Psychiatry. 2002 Oct;73(4):453-5.
Hurtado JM, Gray CM, Tamas LB, Sigvardt KA. Dynamics of tremor-related oscillations in the human globus pallidus: a single case study. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1674-9.
Taha JM, Favre J, Baumann TK, Burchiel KJ. Tremor control after pallidotomy in patients with Parkinson’s disease: correlation with microrecording findings. J Neurosurg. 1997 Apr;86(4):642-7.
Gross RE, Lombardi WJ, Lang AE, Duff J, Hutchison WD, Saint-Cyr JA, et al. Relationship of lesion location to clinical outcome following microelectrode-guided pallidotomy for Parkinson’s disease. Brain. 1999 Mar;122 ( Pt 3):405-16.
Miyagi Y, Shima F, Ishido K, Moriguchi M, Kamikaseda K. Posteroventral pallidotomy for midbrain tremor after a pontine hemorrhage. Case report. J Neurosurg. 1999 Nov;91(5):885-8.
Goto S, Yamada K. Combination of thalamic Vim stimulation and GPi pallidotomy synergistically abolishes Holmes’ tremor. J Neurol Neurosurg Psychiatry. 2004 Aug;75(8):1203-4.
Roberts-Warrior D, Overby A, Jankovic J, Olson S, Lai EC, Krauss JK, et al. Postural control in Parkinson’s disease after unilateral posteroventral pallidotomy. Brain. 2000 Oct;123 ( Pt 10):2141-9.
Kumar R, Lozano AM, Sime E, Halket E, Lang AE. Comparative effects of unilateral and bilateral subthalamic nucleus deep brain stimulation. Neurology. 1999 Aug 11;53(3):561-6.
Hathout GM, Bhidayasiri R. Midbrain ataxia: an introduction to the mesencephalic locomotor region and the pedunculopontine nucleus. AJR Am J Roentgenol. 2005 Mar;184(3):953-6.
Lee MS, Rinne JO, Marsden CD. The pedunculopontine nucleus: its role in the genesis of movement disorders. Yonsei Med J. 2000 Apr;41(2):167- 84.
Jenkinson N, Nandi D, Aziz TZ, Stein JF. Pedunculopontine nucleus: a new target for deep brain stimulation for akinesia. Neuroreport. 2005 Nov 28;16(17):1875-6.
Jenkinson N, Nandi D, Oram R, Stein JF, Aziz TZ. Pedunculopontine nucleus electric stimulation alleviates akinesia independently of dopaminergic mechanisms. Neuroreport. 2006 Apr 24;17(6):639-41.
Zrinzo L, Zrinzo LV, Hariz M [letter]. The pedunculopontine and peripe- duncular nuclei: a tale of two structures. Brain. 2007 Jun;130(Pt 6):e73; author reply e74.
Morris ME, Iansek R, Matyas TA, Summers JJ. Ability to modulate walk- ing cadence remains intact in Parkinson’s disease. J Neurol Neurosurg Psychiatry. 1994 Dec;57(12):1532-4.
Bejjani BP, Gervais D, Arnulf I, Papadopoulos S, Demeret S, Bonnet AM, et al. Axial parkinsonian symptoms can be improved: the role of levodopa and bilateral subthalamic stimulation. J Neurol Neurosurg Psychiatry. 2000 May;68(5):595-600.
Faist M, Xie J, Kurz D, Berger W, Maurer C, Pollak P, et al. Effect of bilateral subthalamic nucleus stimulation on gait in Parkinson’s disease. Brain. 2001 Aug;124(Pt 8):1590-600.
Pahapill PA, Lozano AM. The pedunculopontine nucleus and Parkinson’s disease. Brain. 2000 Sep;123 ( Pt 9):1767-83.
Hamel W, Fietzek U, Morsnowski A, Schrader B, Herzog J, Weinert D, et al. Deep brain stimulation of the subthalamic nucleus in Parkinson’s disease: evaluation of active electrode contacts. J Neurol Neurosurg Psychiatry. 2003 Aug;74(8):1036-46.
Alusi SH, Aziz TZ, Glickman S, Jahanshahi M, Stein JF, Bain PG. Stereotactic lesional surgery for the treatment of tremor in multiple sclerosis: a prospective case-controlled study. Brain. 2001 Aug;124(Pt 8):1576-89.
Herzog J, Hamel W, Wenzelburger R, Pötter M, Pinsker MO, Bartussek J, et al. Kinematic analysis of thalamic versus subthalamic neurostimulation in postural and intention tremor. Brain. 2007 Jun;130(Pt 6):1608-25.
Lanotte MM, Rizzone M, Bergamasco B, Faccani G, Melcarne A, Lopiano L. Deep brain stimulation of the subthalamic nucleus: anatomical, neurophysiological, and outcome correlations with the effects of stimulation. J Neurol Neurosurg Psychiatry. 2002 Jan;72(1):53-8.
Babel TB, Warnke PC, Ostertag CB. Immediate and long term outcome after infrathalamic and thalamic lesioning for intractable Tourette’s syndrome. J Neurol Neurosurg Psychiatry. 2001 May;70(5):666-71.
Aufenberg C, Sarnthein J, Morel A, Rousson V, Gallay M, Jeanmonod D. A revival of Spiegel’s campotomy: long term results of the stereotactic pallidothalamic tractotomy against the parkinsonian thalamocortical dysrhythmia. Thalamus & Related Systems. 2005 Jun;3(2):121-32.
Piallat B, Benazzouz A, Benabid AL. Subthalamic nucleus lesion in rats prevents dopaminergic nigral neuron degeneration after striatal 6-OHDA injection: behavioural and immunohistochemical studies. Eur J Neurosci. 1996 Jul;8(7):1408-14.
Albin RL, Greenamyre JT. Alternative excitotoxic hypotheses. Neurology. 1992 Apr;42(4):733-8.
Luquin MR, Saldise L, Guillén J, Belzunegui S, San Sebastián W, Izal A, Garrido P, Vázquez M. Does increased excitatory drive from the subthalamic nucleus contribute to dopaminergic neuronal death in Parkinson’s disease? Exp Neurol. 2006 Oct;201(2):407-15.
Rodriguez MC, Obeso JA, Olanow CW. Subthalamic nucleus-mediated excitotoxicity in Parkinson’s disease: a target for neuroprotection. Ann Neurol. 1998 Sep;44(3 Suppl 1):S175-88.
Temel Y, Visser-Vandewalle V, Kaplan S, Kozan R, Daemen MA, Blokland A, et al. Protection of nigral cell death by bilateral subthalamic nucleus stimulation. Brain Res. 2006 Nov 20;1120(1):100-5.
Chen L, Liu Z, Tian Z, Wang Y, Li S. Prevention of neurotoxin damage of 6-OHDA to dopaminergic nigral neuron by subthalamic nucleus lesions. Stereotact Funct Neurosurg. 2000;75(2-3):66-75.
Wallace BA, Ashkan K, Heise CE, Foote KD, Torres N, Mitrofanis J, et al. Survival of midbrain dopaminergic cells after lesion or deep brain stimula- tion of the subthalamic nucleus in MPTP-treated monkeys. Brain. 2007 Aug;130(Pt 8):2129-45.
Krack P, Batir A, Van Blercom N, Chabardes S, Fraix V, Ardouin C, et al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson’s disease. N Engl J Med. 2003 Nov 13;349(20):1925- 34.
Rodriguez-Oroz MC, Zamarbide I, Guridi J, Palmero MR, Obeso JA. Efficacy of deep brain stimulation of the subthalamic nucleus in Parkinson’s disease 4 years after surgery: double blind and open label evaluation. J Neurol Neurosurg Psychiatry. 2004 Oct;75(10):1382-5.
Pedroso Ibáñez I, Álvarez Gonzáles L, Macías R, López Flores G, Rodríguez- Rojas R, Tejeiro Amador J, et al. Cirugía lesional como alternativa de tratamiento quirúrgico en la enfermedad de Parkinson (EP). Experiencia del CIREN (Centro Internacional de Restauración Neurológica, Hababa, Cuba) a largo plazo. Rev Mex Neuroci. 2006;7(6):562-72.
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2009 Boris Zurita-Cueva, Fidel Villamar, Paulina Cornejo, Clara Bedoya P, Jorge Altamirano, Mauricio Navarrete Carreño, Osvaldo Navarrete Carreño
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Este artículo se distribuye bajo la licencia Creative Commons Attribution 4.0 License. A menos que se indique lo contrario, el material publicado asociado se distribuye bajo la misma licencia.
