Experiencia en el uso de microrregistro para estimulación cerebral profunda del núcleo subtalámico en pacientes con enfermedad de Parkinson
DOI:
https://doi.org/10.47924/neurotarget2015210Palabras clave:
Enfermedad de Parkinson, Estimulación cerebral profunda, Registro con microelectrodosResumen
Introducción: El uso de Microregistro (MR) para colocación de electrodos de Estimulación Cerebral Profunda (ECP) continúa siendo debatido en la corrección del blanco preoperatorio, complicaciones y resultados. Describimos la experiencia de su uso en el mapeo del Núcleo Subtalámico (NST) en pacientes con Enfermedad de Parkinson (EP).
Materiales y métodos: Se realizó un estudio observacional, retros- pectivo de pacientes con EP tratados desde 2009 hasta 2012. Se describió la discrepancia entre la planeación inicial y la definitiva a través de la suma de los vectores de desviación en los planos X y Y, complicaciones y porcentaje de mejoría, correlacionado con varia- bles demográficas, anatómicas y de la evolución de la enfermedad.
Resultados: Se trataron 43 pacientes, se implantaron 81 electrodos. La desviación media del blanco preoperatorio fue 2,57 mm. El 71,6% de los electrodos tuvieron desviación > 2 mm, 40,7% > 3 mm y el 16% > 4 mm. Ninguna variable se asoció con mayor desviación, con el número de trayectos realizado ni con diferencias en mejoría del UPDRS III. Sólo un paciente presentó hemorragia.
Conclusiones: El uso del MR permitió una corrección significativa del blanco en un amplio porcentaje de casos, la cual podría relacionarse con un mejor resultado clínico. No se asociaron factores al grado de desviación, la frecuencia de complicaciones serias es baja.
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Derechos de autor 2015 José Libardo Bastidas Benavides, Javier Mauricio Serrano Ortiz, Mauricio Rueda Acevedo, José Bareño Silva
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
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